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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53317c916a3d6bb7af9d015df18c4da27e3e79dd330524577fb4e64832600345' 
  AND token = 'QZbHAepl29qb7kAoUOFmWBuFD859ackCZZrgwk/OvJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}