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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779037ad18deabfc6df26cb955b2313dbc54477f50de01f7fa14ede59a3785ca' 
  AND token = 'LZYY0NCY6uG6oQsWRf4oudNjWDGfWBrVrnDasP/F3OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}