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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df53dae807cc9d95692f6f2f87fc0cdac71ffb9662ab57e1da3fe3d913e13525' 
  AND token = '/YGkNRG2qG5dHGaE5eM8600arFZHrVXgkSwUI1RY3DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}