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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4d3130dd5f5088d5871cbb1cb116ace9b766d434bfff18327c579e0af6666c' 
  AND token = 'Xo94W1E+dzM5VhLsDF3dVk8NTT7Mu2OVM2QSlgBEmI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}