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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2dc63a4bc80905a58d24c55ae9722a50c857184b9144c8cafcca66df58cf59' 
  AND token = '/eHVs3hgVOSBQiRRidaT07k7FNZsxb2uZAkP3wC747c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}