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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae6f8ee0ccfb754aedbb5b6a2fe08cec50b0c185b9c19155c981bd184227b439' 
  AND token = 'bdxjIsOpXYkC3vZhlyWt+bI3UyYDab+ded06BcZm+pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}