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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65886acda45e13af31afe5c8cc706ce1c20a2ca8985c24942f1ef92a358f48dc' 
  AND token = 'r/PoTIOejDSBi3oZ3ko7VhvpnhT/khFF8h0unMRoIIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}