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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adc4a6948b6c7333f126fa00b99b7f54342f8a237849efe0a8adc9ed085a1f4' 
  AND token = 'OBhb9twPCDMdXzNtx8Zd0qYqUU8D9fjb/wD0Ib6yp4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}