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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4944c85b44bf98a53957d0e5cbe9deb372e206cae9aa8b8704a1de81a8a44edc' 
  AND token = 'i4zluiU7p4+P2MrTBDdPZHlKAYKxp7TXIYM63mfoNQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}