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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75021dfd53c97945e050d895e44e600e935686fa8788d2cca15d361c722fcb3' 
  AND token = 'RIndDwZLFUKyV2XrslM51U0vt6tmkkLzC2CE7gnBw5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}