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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55baa9a5047d1d3849bc6f61405058787e3f3b924c483a573ac91b605c3ebed' 
  AND token = '2PCbePk7s/VbF0v0bjryefAvolwNRcs9BbV3QPMyy5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}