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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0be59af66fbb27efb50fd04efb1df2aadacadf995ee8f5080ac6f4be022ea1a2' 
  AND token = '0coLAch55ZNY/4pKuwCby85MJrcTLgSSXfvNkMIEtN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}