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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12e9e20c7ad298503e0cb75511ddd1d79b9d095e805bb7435953590aa1bd819' 
  AND token = 'nAZQgCwcxoLOY9M4q04AHIA4fZ1yXKF73gayFwxgCuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}