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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c45400c4d236eb257fb7b00543b2171bb0eee7769eebdcee5721428bf576c5e' 
  AND token = 'TWUb9bUZm8ewEpJDjKkcts8CQkYYKwL//6ausp6UN4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}