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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c430c4e6792974520c7774cee9341944667658d152c563b05690fcf721c38279' 
  AND token = 'JqTrxjSVhLqt3Q0Upbp9jjrEJG8ce5VVHOSWsqKcF0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}