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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745ff515e3d1d65e9da2e5c1484957be1afed532c1e42e7d9f442105c3dc5955' 
  AND token = 'iSaIghckeIOcw9H6eieLo84LA7GFkQIbiHuP2u01yRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}