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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcb1023a6bdcedd6d25e8a4c88f800b434180e583687e92227b125077b90f4b6' 
  AND token = 'HkQV6Cq2C7iRCAxenawu9wwgEa9Tibmu+MvrETgwHXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}