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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349889ca096625e2ccc0e42be1c5d21df162cfc9a442d7ee905e7860c4f90131' 
  AND token = 'GfzFItJE5ka3TUMMYVhsRmiMk1+gLD8v3zDtMjOW9sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}