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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c00c812d4a77818fb6e505b111bb3149fc3e68035e28f54fa25145aa791630f5' 
  AND token = '2baG0nITOcjpvVWfCGe/BQ2opq9BvEdU3j4LgV8MLAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}