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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c874eddb8aa7fea8217da2e936cfc3d6e93d01d914b8e4195912aadb46099946' 
  AND token = '+OsxO6aUxjyM4Rv37K1Vj4fpM+98FG28mrJsO8/tRsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}