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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ccbc498471bf5991b6190a9962fb7563c1eadf590a75682e7a816969da039b6' 
  AND token = 'XfAmgDSH4NsVk/2OXcedspGOXML9b0mb6xLjjwJ3RbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}