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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0515f84013b4671855de687f7e1a84f04543f851139e44ad5def0a6900e2c3b6' 
  AND token = 'd3AySkDgkEzO/SqdtcNuxlYBjNpKVZfZ+GRrQoL2SSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}