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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f891efc7274f4d3d9a2b661716562a29cda8a06b7bbd64c1f192306eec5843a6' 
  AND token = 'fCX75ETHBDfOcH37gTug8/KWFUoMs3S+D8gdnvvqLaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}