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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a2c6117f95c59cba45346f0a27a80b1fd54533a688dcf7978f157e63b80b51' 
  AND token = '9Q0HM0F8Sq1WGcStyt9yzeew/wihGgxkQZa8542o6DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}