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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b022156938d287627ad7f2b55f5972bd66637db6e698ab612070204d748da3' 
  AND token = 'f63/mgz8d/3TjcDu6/SWQhcECNmeEgOhYZBJ2WZ33cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}