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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8696b48025686ec40417eea26b14ed5505cdb9fff7c462ddec1f8c95c1407f' 
  AND token = 'oZrDmWoN2NDcPS4KntV+MX67jFWsceJEw5+1DDcbbG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}