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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b424cd825a09069002439d8279fbd8d3f9ee99cf18e1c858017f5650463ca8' 
  AND token = 'PD10jBAAAqZouNYgbgOE0tFj35h7Lu/f0Aq8kQg50bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}