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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c1b38e034c5890532906b0ff78840d0c91f19838c349ca5b78d150a0117f35' 
  AND token = 'vEUa67dDreHzh+aa33UYNRiT6IPZvzCx53wdKmNW9DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}