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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83baf59afb5621c14dfc450daf72e7e5c3b3bf6555386f4e17ec19f36027e111' 
  AND token = 'bQUW2M0MiYWGa2DLdyUq4xmGpgBBR+ihqnm/56ftHec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}