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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b50ae63cadec02d430f25a50742d96f5eb516f6f0aaa37c682de90aa1ac53cc' 
  AND token = 'G7DLUp8lFWaQ3XG2V7sYQRf7yH82n8VrFn4MiHIDGTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}