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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0554f584ecc6ca144bc811a3530b8a02abb13d91190e60d9ad30e81b1e842158' 
  AND token = 'zR+W0pDV5mJvtYm/K48X6hQFiKCuRSZSg2wR8TfWq3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}