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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c3f43d654a328924d2fdeed24ad6eeaf0f8b051cc1ff13911812aca3279c4de' 
  AND token = 'cpQ/IAWFFFIA9Gf6WKual4EISBZTDMI5NQ2rRgn7A0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}