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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b9cdb8ebf5d6fa3ff3ffe55cb467340cf8a3440db2df696814558d0291071a' 
  AND token = 'TDXLbHNO+TGSn58COAv8M1MDtQFzcr4Lj8FbdvqTBPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}