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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '206b2aae5ea977b8064779acc1f4834d5424eb3663b609f175022144049b657a' 
  AND token = 't+ZnKo/yv14QX4C/1V3i9njTem28T5I4GuqyEhTH0HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}