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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4109bdaf10022503e60d201ec2a2483cf10ccec9cc7d4d248288b47f65c385b5' 
  AND token = 'iCJc7wI5lqby3Ns7SZWbgmYWEzXGPdCF7Fjyaf9qF4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}