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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c582b2aa46eccb1aeb537be258eca0114bbd2bac9412dfed6e44b6fe37389f' 
  AND token = 'I2rMNS9Y6KOugBmj1Z3fNLsLSdQNwKOg/v6382JWWrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}