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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c596e249e75cdfe17120081e6e4f83379ff7c91141b87d100e2d3e5c7acaa995' 
  AND token = 'cNmUo+rH+Tfxr/whsrKG8EHoYi0HRMiBaN8JvskXgZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}