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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2208fcd651c81fbc0b236d69d716ed85ade0fae9835eff905e691b6699025142' 
  AND token = 'kged9XIujNu853KR9n+k5eatHVlqqyBmk4V6EP4Oxhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}