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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd3be3f9abfc5953d93a270685121cba5d56b8f92b1a37ca2e61e1bc8d1319d6' 
  AND token = '8MbOyEb+bSz3nyDd5NYBBZdb99g86Zd4mvC6KU2rA4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}