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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de40e99dfdca2001e2e91c63c22df44fbd1f6bb7f8799f12e6744508378088da' 
  AND token = 'OtiWj8Q6Pf33I/i8dCybV/C3h8J4udbtXcnFl/qbfZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}