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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b8b30c8d7bf104bbbd97e183baac3316fd4abaa3208f7f147b510a124aafa9' 
  AND token = 'KBISvfzlmqWywfW84+2nkgvXvVAG7RaAKy0VwzfxIZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}