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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f2501fd9549c8c7fe8b9535e37807dfb12360df11b788ba5410cadb7ab37be8' 
  AND token = '8PS/gL8t+rxnkUPG3oFHheEMYJFZuQmsBbois5fslbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}