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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6479e2330780920938168bfc86ca811f63cf7bf68061445ff8c948597f339d9' 
  AND token = '4PXI213mOYM1iVfDMQGelm8TfZoMCbDEX/34uX1zDdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}