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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46bd78a89f40ecbf14637e22d000ac47f659405f1cb66a331905c3299d1b67f5' 
  AND token = 'S3lGmuSrie6u3Z8w1tsz7r3m6CAM/nySP46ghoPHz9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}