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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180e30490b903790303b3ad5e59299e4f154938de8528dce06dfdd7b0ed4da87' 
  AND token = '9oMuy0JEz84oOZDRfw/oMv8Tyzj74jLmAdmUJC2qIXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}