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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647f3c8fb5a4b47a7359747a1b3e6367d8ef3563c31f9de6e452d9b914315da3' 
  AND token = '2lPbE/SFkRl8XY6g+dplOjfzIuy3a8Am0Jr3uRJ9F/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}