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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b263de4ec3d54a17500458a114784805d0600b2abb923a1c6620541c83ace287' 
  AND token = '9Rr6V9YiItbfjKI8dTDeDq5Eh5EwE65oIsKoXWS4qmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}