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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f35dbab9753166c4add868fa46a68f9df1ff803331241a5b8e8c8b386bfd43' 
  AND token = 'XNZq2nSvNX3juzpiW43bdpVU5G6WTv82V0UgQY66BmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}