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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc088dbd8e728113d93bddda6c29145fc52ba1f91e28c115899ace69b7ca7d3' 
  AND token = 'SC3If2gR7oYXbNREhkf8K1Rmr16v5Up8CvXM4NoGT80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}