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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c646bc677297f606bf59e7df8c7a47516822ae04b8df34e3d4de993fc5b64602' 
  AND token = 'vrXWcXNi53hwuMny3W9o4CufyHg7NS0vvBdvDAq+SCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}